Flaxseed to reduce plasma cholesterol and the formation of atherosclero

Regarding the study linseed reduces blood plasma cholesterol and atherosclerotic lesion formation in ovariectomized florid Syrian hamsters, the research question for Lucas et al. (2004) study is Can flaxseed reduce plasma cholesterol and the formation of atherosclerotic lesion in women who are deficient in ovarian hormones or menopausal women? According to the study, in menopausal women, the deprivation of ovarian hormones will increase the level of plasma cholesterol and the attempt of plaque formation which lead to cardiovascular disease (CVD). Previously, hormone replenishment therapy (HRT) was used to solve this problem. However, it is related to an increased risk of some honorable diseases such as ovarian cancer and breast cancer therefore, a lot of women are turning to a safer way to deal with this problem. Recently, functional foods, foods which have the potential for health protection, are considered alternatives to use for reduction CVD risks, and flaxseed is one of those which is used to lower factors that cause CVD. Since it is rich in lignans, -linolenic savage (ALA) and soluble fiber which can lower cholesterol level, flaxseed would be beneficial for decreasing CVD risks in postmenopausal women. From previous animal and gracious studies, we know that flaxseed has the potential to reduce concentrations of cholesterol. Moreover, it can in like manner keep on atherosclerosis by interacting with the vessel wall. However, the effect of flaxseed in reducing plasma cholesterol and atherosclerotic lesion formation associated with ovarian hormone privation has not been investigated (Lucas et al., 2004). For these reasons, this study focused on the dose-dependent effect of flaxseed on cholesterol concentrations and atherosclerotic lesion formation. S... ...study and methods to measure and analyze data. Ovariectomized hamsters were proper representatives of postmenopausal women, since later on ovariectomy, their plasma cholesterol and the form ation of lesions were also increased. Moreover, the authors referred to related studies to develop the experiments and this also provides information about the importance of the project. However, samples collected during the study had to be unbroken and analyzed later therefore, this may affect their condition and an accuracy of the results. deeds CitedLucas, A. E., Lightfoot, A. S., Hammond, J. L., Devareddy, L., Khalil, A. D., Daggy, P. B.,Smith, J. B., Westcott, N., Mocanu, V., Soung, Y. D., Arjmandi, H. B. (2004). Flaxseedreduces plasma cholesterol and atherosclerotic lesion formation in ovariectomized Golden Syrian hamsters. Atherosclerosis, 173, 223-229.